Dry Martini for lipids
- Last Updated: Monday, 23 May 2016 11:18
Try out the next flavor of the Martini force field for lipids: Dry Martini. Still without olives.
In this version of Martini, water beads were completely removed from our simulation boxes. We adapted the interactions between beads by slightly tweaking the interaction levels and tuning some bonded parameter to reproduce the properties observed with the standard Martini force field. The new force field developed has been shown to nicely reproduce bilayer properties for a large variety of lipids.
Dry Martini is so far available only for lipids. A couple of small membrane proteins have been shown to perform equivalently compared to the regular Martini model; adaptation for proteins in (dry) solution is still in progress.
Curious? Excited? Download the parameter files and run your first Martini simulations without aqueous solvent!
Dry_Martini_v2.1 (Updated 23 May 2016, all "O"-lipids now use the 4 bead oleyl tail parameters and PO tails are in correct order.)
Wanna read more? Check this out:
C. Arnarez, J.J. Uusitalo, M.F. Masman, H.I. Ingólfsson, D.H. de Jong, M.N. Melo, X. Periole, A.H. de Vries, S.J. Marrink
Dry Martini: coarse grained implicit water force field for (bio)molecular simulations, JCTC (doi: 10.1021/ct500477k)